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Writer's pictureRIck LeCouteur

Side Effects: Language, perception, and reality



When we hear the term side effects, it often carries an implicit assumption:

these effects are secondary, unintentional, and separate from the primary purpose

of a medication or treatment.

 

But are they truly side effects, or is this a convenient way of downplaying their significance?

 

Perhaps a better terms might be undesirable or unwanted effects.

 

The Nature of Side Effects

 

Every medication or treatment interacts with the body in complex ways. The same mechanisms that provide therapeutic benefits often affect other systems. These effects are not on the side; they are intrinsic to how the treatment works. For instance:

 

  • Aspirin helps reduce pain and inflammation but can also irritate the stomach lining, leading to ulcers or bleeding.


  • Antibiotics kill harmful bacteria but can also disrupt gut flora, causing digestive issues.


These outcomes are not incidental. They are part and parcel of how the drug interacts with the body's biochemistry.

 

The Language Problem

 

Describing these effects as side effects creates a psychological separation.

 

It suggests that these outcomes are peripheral or avoidable, rather than inherent risks. This framing might comfort patients but could lead to misunderstandings about the risks involved.

 

  • Unwanted Effects: This phrase might better communicate the reality. These effects are not tangential; they are part of the deal. For instance, chemotherapy is effective because it targets rapidly dividing cells - but that includes healthy cells like those in hair follicles and the digestive tract.


  • Secondary Effects: While technically accurate, this term still implies a hierarchy where the primary effect is king, and everything else is a minor inconvenience.

 

Reframing Side Effects

 

Acknowledging that all effects - desired or not - are integral to a treatment can lead to better communication between healthcare providers and patients. For example:


  • Informed Consent: Patients deserve clear explanations about all potential outcomes of a treatment. Recasting side effects as "associated effects" may prompt a more balanced discussion.


  • Shared Decision-Making: When patients understand that so-called side effects are part of the package, they can better weigh the benefits against the risks.


  • Empathy and Management: Re-framing these effects as part of the treatment process encourages empathy and a focus on managing them effectively.

 

Case Study: Vaccines

 

Vaccines often cause mild reactions - fever, soreness, or fatigue. These aren’t side effects; they’re evidence that the immune system is responding. Rebranding these reactions as expected effects might shift perceptions from fear to understanding.

 

Rick’s Commentary

 

Side-effects is a misleading term. Such effects aren’t peripheral, accidental,

or dismissible - they’re simply effects.

 

Some are desirable, others are not. Re-framing the language we use around treatments could lead to greater transparency, understanding, and trust in medical interventions.

 

Next time you hear about side effects, ask yourself:

Are they truly on the side, or are they part of the full picture?

 

 

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